Sign In
The user name and password you entered does not match
the information we have on file.
Forgot your password?
Contact us
Please enter a valid code.
Contact us
Showing Results for childhood cancer
Narrow Results
Topics
Content Types
NCI Clinical Trials
Looking for trials? Go to NCI and browse 8,000+ trials
107 Search Results
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Perry’s The Chemotherapy Source Book, 5e
Perry’s The Chemotherapy Source Book, 5e
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Principles of Molecular Diagnostics and Personalized Cancer Medicine
Principles of Molecular Diagnostics and Personalized Cancer Medicine
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 108. Thyroid Tumors >
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 122. Molecular Biology of Childhood Cancers >
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 122. Molecular Biology of Childhood Cancers >
Several important issues have arisen as a result of the identification of germ line mutations of tumor suppressor genes in cancer-prone individuals and families. These include ethical questions of predictive ...
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 122. Molecular Biology of Childhood Cancers >
With the identification of alterations in a variety of molecular signaling pathways, including activated growth factor signaling pathways (e.g., IGF-2) and altered tumor suppressor pathways (e.g., retinoblastoma), it has become ...
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 123. Solid Tumors of Childhood >
The management of childhood malignant solid tumors is complex and requires an integrated multidisciplinary approach that often involves various treatment modalities such as surgery, radiotherapy, and chemotherapy. Surgery plays a ...
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 165. Gonadal Dysfunction >
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 167. Second Primary Cancers >
Survival rates for children with cancer have increased substantially over the past 3 decades, with this rapidly growing population at lifelong risk for the late effects of cancer treatment. In ...
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 172. Sexual Problems >
Childhood cancers and their treatments can also have an impact on the sexual development and function of adolescents and young adults. Zebrack et al.127 found that although most survivors report ...
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Chapter 1. The Cancer Problem in Children >
In 1900, cancer trailed typhoid fever, malaria, smallpox, measles, scarlet fever, whooping cough, diphtheria, croup, influenza, dysentery, erysipelas, tuberculosis, sexually transmitted disease, meningitis, acute bronchitis, pneumonia, accidents, birth injuries, and ...
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Chapter 1. The Cancer Problem in Children >
The relative frequency of the various types of childhood cancer is influenced by whether we are examining incidence or mortality and by how we stratify by age, sex, or nation. ...
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Chapter 1. The Cancer Problem in Children >
The mortality rate from childhood cancer has fallen dramatically in the United States. Particularly impressive gains have been posted for acute lymphocytic leukemia (ALL), bone tumors (predominantly osteosarcoma and Ewing ...
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Chapter 1. The Cancer Problem in Children >
Some data suggest that the overall incidence of childhood cancer is rising in the United States. Experts disagree about what might account for this alleged increase. Some have asserted that ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 17. Intraoperative Radiotherapy >
IORT in pediatric patients represents a means of improving precision in dose deposition, protection of normal uninvolved tissues and, moreover, radiation treatment design in which the EBRT can be either ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 18. Particle Beam Radiotherapy >
Investigators at PSI looked at the potential influence of improved dose distribution with proton beams compared to conventional or IMRT x-ray beams on the incidence of treatment-induced secondary cancers in ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 22. Clinical Aspects and Applications of High–Dose-Rate Brachytherapy >
LDR brachytherapy has been used in children to reduce the deleterious effects of EBRT (37,40,49). However, LDR brachytherapy is difficult to perform in young children and infants because they require ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 31. Malignant Neoplasms Associated with the Acquired Immunodeficiency Syndrome >
Where available, the use of antiretroviral drugs in HIV-infected pregnant women and their infants has resulted in a dramatic decline in perinatally acquired HIV infection (43). However, maternal-infant transmission remains ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 34. Spinal Canal >
Children diagnosed and treated for primary tumors of the spinal canal present special prognostic concerns and apprehensions because of the increased potential for treatment-induced morbidity. The spinal cord in children ...
Diseases of the Breast
Diseases of the Breast
Chapter 92. Breast Cancer in Younger Women >
Young women with a history of treatment for childhood cancer, in particular those treated with chest (“mantle”) irradiation for Hodgkin's Disease, are at dramatically increased risk of early onset breast ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 11. Minimally Invasive Surgery for Cancer >
Minimally invasive techniques have been used in many areas of pediatric surgery, and its utility extends to the diagnosis and treatment of malignancy. Most pediatric solid tumors are treated with ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Public health surveillance involves the systematic collection, analysis, and interpretation of outcome-specific health data and the timely dissemination of the findings to prevent and control disease or injury. Surveillance systems ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Childhood cancer is relatively uncommon, with approximately 1 to 2 children in every 10,000 children aged 14 years and younger diagnosed in the United States each year.7 Despite the rarity ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Figure 1.2 compares the distribution by percentages of the cancers that occurred among 0- to 14-year-olds and 15- to 19-year-olds for the years 1973 to 2006, whereas Table 1.1 provides ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Survival rates for children 0 to 14 years of age have improved dramatically since the 1960s when the overall 5-year survival rate after a cancer diagnosis was estimated as 28%.9 ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Some epidemiologic studies, such as randomized intervention trials and randomized controlled clinical trials, follow the principles of scientific experimentation in which a treatment or intervention of interest and the control ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Classical or traditional epidemiology, as discussed previously, permits epidemiologists to evaluate risks and causal roles of environmental factors in cancer. Molecular epidemiology, a hybrid of epidemiology and molecular biology, enables ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Environmental risk factors for adult cancer generally involve long latency periods from exposure commencement to clinical onset of disease. Cigarette smoking illustrates this point: Smoking usually starts during adolescence, but ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Although knowledge about childhood cancer continues to increase, there is much work to be accomplished before reliable preventative measures can be recommended. In this brief overview, we have discussed the ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
Table 1.1 shows the incidence of cancer by gender for children (<15 years) and adolescents (15 to 19 years). For both 0- to 14-year-olds and 15- to 19-year-olds, a male ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
For many adult cancers, black Americans have higher incidence rates than do white Americans. However, for children and adolescents, the incidence of cancer among white children was approximately 40% higher ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer >
It is common for clinicians to encounter parental concern about multiple cancer occurrences in their child’s community. The implication, of course, is that a shared environmental exposure is responsible for ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 2. Childhood Cancer and Heredity >
Several studies have suggested that 4% to 10% of childhood cancers result from inherited genetic mutations, making it essential for pediatricians and pediatric oncologists to recognize clinical criteria suggestive of ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 3. Molecular and Genetic Basis of Childhood Cancer >
The cancers of childhood are largely the products of somatically acquired genetic abnormalities that modify protein function. The classes of proteins affected by these changes include growth factors and their ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 6. Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer >
Certain children are at increased risk for developing cancer. They include children with the genetic predispositions to cancer that are discussed in Chapter 2, such as Down syndrome, neurofibromatosis, and ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 6. Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer >
Various studies have evaluated factors that contribute to the lag time to diagnosis of cancer. A recent review grouped these delays into three categories: disease, patient/parent, and health care related.31 ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 6. Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer >
As previously noted, in almost all cases, diseases other than cancer may produce identical nonspecific symptoms at presentation. Although assessment for these findings does not always require an evaluation for ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 6. Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer >
With the exception of the rare true emergency, optimal treatment for a malignancy can begin only after the tumor has been accurately diagnosed and the extent of disease precisely defined. ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 6. Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
Epithelial origin cancers (carcinomas) are unusual in children but common in adults. In contrast, retinoblastoma is associated with young children and unknown in adults.14 It is important to remember that ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
Pathology has been transformed by new diagnostic technology, instruments, and knowledge gained from advances in immunology, molecular biology, genomics, and proteomics during the past few decades. This has changed the ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
Many pediatric tumors are associated with specific age ranges (Fig. 8.2). Overall cancer incidence is highest just after birth and declines to its lowest point by 10 years of age. ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
Genetic factors, such as inherited gene defects, are not uncommon in childhood tumors. The prototypic example is familial versus sporadic retinoblastoma.17 Children with familial tumors possess a constitutional mutation in ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 8. Diagnostic Pathology of Pediatric Malignancies >
The functional human genome is composed of three major categories: DNA, RNA, and protein. Potential diagnostic methods based on each of these categories are illustrated in Figure 8.25 and are ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 9. Imaging Studies in the Diagnosis and Management of Pediatric Malignancies >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 9. Imaging Studies in the Diagnosis and Management of Pediatric Malignancies >
Assignment of patients by risk group into stratified prognostic categories is a fundamental feature of the therapeutic protocols of many pediatric malignancies. Treatment intensity can be adapted to minimize toxicity ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 9. Imaging Studies in the Diagnosis and Management of Pediatric Malignancies >
Delineation of the extent of a tumor and its anatomic relationships to vital structures is particularly important when surgery or radiation therapy is planned. Noninvasive imaging studies recommended for tumor ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 9. Imaging Studies in the Diagnosis and Management of Pediatric Malignancies >
With any cancer treatment regimen, there is an obvious desire to know whether the treatment is having the intended effect. Tumor response assessment can have different endpoints, depending on the ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 11. Molecularly Targeted Therapies and Biotherapeutics >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 11. Molecularly Targeted Therapies and Biotherapeutics >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 17. Cancer Clinical Trials: Design, Conduct, Analysis, and Reporting >
Cancer clinical trials are conventionally categorized into three types.2 A phase 1 trial investigates the adverse events associated with a particular agent or combination of agents and determines the maximum ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 18. Regulating Patient Safety in Cancer Treatment >
Several studies have demonstrated that errors can occur in every medical setting; however, vulnerable populations and high-risk procedures add additional challenges. Most publications describe interventions in the emergency room or ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 42. Pain and Symptom Management >
There are approximately 12,400 children diagnosed with cancer each year in the United States. As recently as the 1970s, a diagnosis of childhood cancer was considered uniformly fatal. Today, there ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 45. Psychiatric and Psychosocial Support for the Child and Family >
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 45. Psychiatric and Psychosocial Support for the Child and Family >
As treatment continues, fears related to the disease become less prominent, and other concurrent stresses are perceived as more troublesome.75 Parents often find themselves in a quandary in deciding how ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 45. Psychiatric and Psychosocial Support for the Child and Family >
Cancer disrupts the typical avenues of social activity and forces the young patient to temporarily relinquish usual roles for that of a patient in an unfamiliar system of doctors and ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 45. Psychiatric and Psychosocial Support for the Child and Family >
The effects of childhood cancer on the healthy siblings within the family deserve special attention. While the effects of illness on families and individual family members is multifaceted and reciprocal,64,65,296 ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 45. Psychiatric and Psychosocial Support for the Child and Family >
Our growing multicultural society presents health care providers with a difficult task of providing appropriate care for individuals who have diverse life experiences, beliefs, value systems, religions, languages, and notions ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 47. Late Effects of Childhood Cancer and its Treatment >
The Institute of Medicine has recognized the need for a systematic plan for lifelong surveillance that incorporates risks based on therapeutic exposures, genetic predisposition, health-related behaviors, and comorbid health conditions.8 ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 48. Educational Issues for Children with Cancer >
School is the work of childhood. It presents each child with a daily opportunity to feel productive, master the environment, learn social skills, and receive peer support. As Maul-Mellott and ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 48. Educational Issues for Children with Cancer >
In previous editions of this chapter we used, as a framework for our discussion of school re-entry, a three-phase model first described by Madan-Swain and colleagues.28 Here we use a ...
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 53. Pediatric Oncology in Countries with Limited Resources >
Although there are few, truly population-based cancer registries in developing countries, it is clear (especially from the work of the International Agency for Research on Cancer—IARC)5 that the reported annual ...
Human Radiation Injury
Human Radiation Injury
Chapter 15. Effect of Radiation on the Embryo and Fetus >
The association between in utero exposure to radiation and development of leukemia and other childhood cancers has been recognized for over 30 years.10 Whether the carcinogenic effects for a given ...
Perry’s The Chemotherapy Source Book, 5e
Perry’s The Chemotherapy Source Book, 5e
Chapter 24. Second Malignancies after Chemotherapy >
Between 1975 and 2002, mortality from childhood cancer has declined by 45.5% with improvements in therapy. Various cohort studies have provided data regarding the health of long-term survivors, including the ...
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Chapter 65. Long-Term Survivorship: Late Effects >
Tables 65.1 and 65.2 display some of the more common late effects associated with radiation and chemotherapy and further details are provided in the section below. Table. 65.3 lists the ...
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Principles and Practice of Palliative Care and Supportive Oncology, 4e
Chapter 65. Long-Term Survivorship: Late Effects >
The risk and severity of some, albeit not all, adverse outcomes for which childhood cancer survivors are at risk changes throughout their lifespan (144). Table. 65.4 shows the components of ...
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 123. Solid Tumors of Childhood > Solid Tumors of Childhood: Introduction
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 165. Gonadal Dysfunction > Characteristics of Gonadal Toxicity
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 169. Cancer Survivorship > Promotion of Adjustment and Healthy Lifestyles
Pediatric Radiation Oncology
Pediatric Radiation Oncology
Chapter 1. The Cancer Problem in Children > Relative Frequency of the Various Types of Childhood Cancer
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 1. Epidemiology of Childhood Cancer > Overall Cancer Frequency and Incidence by Type of Cancer for Children and Adolescents
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 6. Clinical Assessment and Differential Diagnosis of the Child with Suspected Cancer > Introduction
Principles and Practice of Pediatric Oncology
Principles and Practice of Pediatric Oncology
Chapter 49. Palliative Care for the Child with Cancer > Integrating Palliative Care
Human Radiation Injury
Human Radiation Injury
Chapter 9. Optimization of Radiotherapy Treatment Delivery Technology to Minimize Radiation Injury > Reducing Radiation Injuries to Defined “Organs at Risk” Receiving High-To-Intermediate Doses
Human Radiation Injury
Human Radiation Injury
Chapter 25. Vascular Effect of Radiation in the Central Nervous System > Cerebrovascular Disease in Children
Didn't find what you were looking for?
Run a full-text search on 'childhood cancer'
What do you think of LWWOncology?
Share Your Feedback
More Results
Journal Results from PubMed
View More on PubMed >