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Showing Results for pancreatic resection
14 Search Results
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 82. Cancer of the Pancreas >
Operative Treatment
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 82. Cancer of the Pancreas >
Patterns of Failure in Resected Pancreatic Cancer
The pattern of failure in surgically resected pancreatic cancer has been well established. Prior to the routine delivery of adjuvant therapy, Tepper et al.102 reviewed the records of 145 patients ...
Cancer: Principles & Practice of Oncology
Cancer: Principles & Practice of Oncology
Chapter 82. Cancer of the Pancreas >
Resection of Locally Advanced Tumors
There is a widespread perception that the delivery of preoperative or neoadjuvant therapy (generally using chemoradiation) may down-stage locally advanced, unresectable pancreatic tumors and allow for subsequent resection. Unfortunately, the ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 56. Cancer of the Pancreas >
Operative Considerations
More than 80% of patients present with advanced disease that is not amenable to curative resection (52,85), and 66% of patients are 65 years of age or older. The standard ...
Perez and Brady’s Principles and Practice of Radiation Oncology
Perez and Brady’s Principles and Practice of Radiation Oncology
Chapter 56. Cancer of the Pancreas >
Areas of Failure and Cause of Death
For patients with locally unresectable tumors or metastatic disease, death usually results from hepatic failure caused by biliary obstruction by local tumor extension or hepatic replacement by metastases. For the ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 35. Cancer of the Pancreas: Surgical Management >
Resection of Pancreatic Cancer
The pancreas has long been an organ that has defied surgical intervention. Walter Kausch (22) is credited for performance of the first pancreaticoduodenal resection, reported in 1912. The lead of ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 35. Cancer of the Pancreas: Surgical Management >
Outcomes After Pancreatic Resection
Perhaps the greatest surgical advance in pancreatic resection over the past 3 decades is the dramatic decrease in perioperative mortality. As recently as the 1970s, mortality after pancreatic resection approached ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 35. Cancer of the Pancreas: Surgical Management >
Outcomes after Pancreatic Resection
I agree with the authors that a pancreatic fistula is one of the more significant complications of the Whipple procedure and also agree that the use of octreotide, fibrin glue, ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 36. Cancer of the Pancreas: Adjuvant and Neoadjuvant Therapy >
Adjuvant Therapy: Chemotherapy and Chemoradiation
Several randomized controlled trials of adjuvant treatment following curative resection of pancreatic cancer have been reported (7 − 11) (Table 36.1). In the United States, data supporting multimodality therapy come ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 36. Cancer of the Pancreas: Adjuvant and Neoadjuvant Therapy >
Neoadjuvant Therapy
In many of the trials of adjuvant therapy, a significant proportion of patients initially enrolled failed to complete their adjuvant protocol or experienced treatment commencement delays. Prolonged postoperative course and/or ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 36. Cancer of the Pancreas: Adjuvant and Neoadjuvant Therapy >
Intraoperative Radiation
The rationale for intraoperative radiation is that high doses of radiation can be delivered while bowel and other normal tissues can be retracted or shielded. Experience with intraoperative radiation is ...
Principles and Practice of Surgical Oncology
Principles and Practice of Surgical Oncology
Chapter 36. Cancer of the Pancreas: Adjuvant and Neoadjuvant Therapy > Locally Advanced Unresectable Disease
Induction therapy has been shown in various relatively small single-institution ...
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